4I41
Crystal Structure of human Ser/Thr kinase Pim1 in complex with mitoxantrone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase pim-1 | polymer | 281 | 32537.9 | 1 | UniProt (P11309) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | B, C (A) | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE | non-polymer | 444.5 | 2 | Chemie (MIX) | |||
| 3 | D (A) | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence modifications
A: 29 - 305 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Pro 26 | - | expression tag |
| His 27 | - | expression tag |
| Met 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32537.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 889.0 | |
| All* | Total formula weight | 33426.8 |
