4I0K

Crystal structure of murine B7-H3 extracellular domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CD276 antigen	polymer	222	24265.0	1	UniProt (Q8VE98) Pfam (PF07686) Pfam (PF22705) In PDB	Mus musculus (mouse)	B7 homolog 3, B7-H3, Costimulatory molecule
2	B	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G22573RC)
3	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
4	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5		water	water		18.0	5	Chemie (HOH)

Sequence modifications

A: 34 - 247 (UniProt: Q8VE98)

PDB	External Database	Details
Thr 248	-	expression tag
Gly 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	24265.0
Branched	Number of molecules	1
	Total formula weight	748.7
Non-Polymers*	Number of molecules	3
	Total formula weight	413.3
All*	Total formula weight	25427.0

*Water molecules are not included.