4HVP
Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 Angstroms resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV-1 PROTEASE | polymer | 99 | 10764.6 | 2 | UniProt (P03369) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | C (B) | N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide | non-polymer | 771.0 | 1 | BIRD (PRD_000398) Chemie (2NC) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P03369)
| PDB | External Database | Details |
|---|---|---|
| Aba 67 | Cys 123 | conflict |
| Aba 95 | Cys 151 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21529.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 771.0 | |
| All* | Total formula weight | 22300.3 |
