4HTX
Crystal structure of PDE2 catalytic domain in complex with BAY60-7550
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | cGMP-dependent 3',5'-cyclic phosphodiesterase | polymer | 342 | 39965.8 | 4 | UniProt (O00408) Pfam (PF00233) | Homo sapiens (human) | Cyclic GMP-stimulated phosphodiesterase, CGS-PDE, cGSPDE |
| 2 | E, H, K, N (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, I, L, O (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | G, J, M, P (A, B, C, D) | 2-(3,4-dimethoxybenzyl)-7-[(2R,3R)-2-hydroxy-6-phenylhexan-3-yl]-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one | non-polymer | 476.6 | 4 | Chemie (19F) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 705 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 159863.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2265.1 | |
| All* | Total formula weight | 162128.2 |
