4HTF

Crystal structure of S-adenosylmethionine-dependent methyltransferase from Escherichia coli in complex with S-adenosylmethionine.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	S-adenosylmethionine-dependent methyltransferase	polymer	285	33162.1	1	UniProt (Q8XDG3) Pfam (PF13847) In PDB	Escherichia coli
2	B	S-adenosylmethionine-dependent methyltransferase	polymer	285	33146.1	1	UniProt (Q8XDG3) Pfam (PF13847) In PDB	Escherichia coli
3	A, B	S-ADENOSYLMETHIONINE	non-polymer		398.4	2	Chemie (SAM)
4	A, B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	A	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
6	B	BETA-MERCAPTOETHANOL	non-polymer		78.1	1	Chemie (BME)
7		water	water		18.0	369	Chemie (HOH)

Sequence modifications

A: 1 - 261 (UniProt: Q8XDG3)

PDB	External Database	Details
Mse -23	-	EXPRESSION TAG
His -22	-	EXPRESSION TAG
His -21	-	EXPRESSION TAG
His -20	-	EXPRESSION TAG
His -19	-	EXPRESSION TAG
His -18	-	EXPRESSION TAG
His -17	-	EXPRESSION TAG
Ser -16	-	EXPRESSION TAG
Ser -15	-	EXPRESSION TAG
Gly -14	-	EXPRESSION TAG
Val -13	-	EXPRESSION TAG
Asp -12	-	EXPRESSION TAG
Leu -11	-	EXPRESSION TAG
Gly -10	-	EXPRESSION TAG
Thr -9	-	EXPRESSION TAG
Glu -8	-	EXPRESSION TAG
Asn -7	-	EXPRESSION TAG
Leu -6	-	EXPRESSION TAG
Tyr -5	-	EXPRESSION TAG
Phe -4	-	EXPRESSION TAG
Gln -3	-	EXPRESSION TAG
Ser -2	-	EXPRESSION TAG
Asn -1	-	EXPRESSION TAG
Ala 0	-	EXPRESSION TAG

B: 1 - 261 (UniProt: Q8XDG3)

PDB	External Database	Details
Mse -23	-	EXPRESSION TAG
His -22	-	EXPRESSION TAG
His -21	-	EXPRESSION TAG
His -20	-	EXPRESSION TAG
His -19	-	EXPRESSION TAG
His -18	-	EXPRESSION TAG
His -17	-	EXPRESSION TAG
Ser -16	-	EXPRESSION TAG
Ser -15	-	EXPRESSION TAG
Gly -14	-	EXPRESSION TAG
Val -13	-	EXPRESSION TAG
Asp -12	-	EXPRESSION TAG
Leu -11	-	EXPRESSION TAG
Gly -10	-	EXPRESSION TAG
Thr -9	-	EXPRESSION TAG
Glu -8	-	EXPRESSION TAG
Asn -7	-	EXPRESSION TAG
Leu -6	-	EXPRESSION TAG
Tyr -5	-	EXPRESSION TAG
Phe -4	-	EXPRESSION TAG
Gln -3	-	EXPRESSION TAG
Ser -2	-	EXPRESSION TAG
Asn -1	-	EXPRESSION TAG
Ala 0	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66308.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1126.2
All*	Total formula weight	67434.3

*Water molecules are not included.