4HTC
THE REFINED STRUCTURE OF THE HIRUDIN-THROMBIN COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | ALPHA-THROMBIN (SMALL SUBUNIT) | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | |
| 2 | B (H) | ALPHA-THROMBIN (LARGE SUBUNIT) | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (I) | HIRUDIN VARIANT 2 | polymer | 65 | 6917.5 | 1 | UniProt (P09945) Pfam (PF00713) | Hirudo medicinalis (medicinal leech) | |
| 4 | D (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E, F, G (L, H, I) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
I: 1 - 65 (UniProt: P09945)
| PDB | External Database | Details |
|---|---|---|
| Lys 47 | Asn 54 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 40794.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 41015.5 |
