4HS8
Hepatitus C envelope glycoprotein E2 fragment 412-423 with humanized and affinity-matured antibody hu5B3.v3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E2-peptide | polymer | 16 | 1727.9 | 1 | UniProt (Q9YK84) | Hepatitis C virus | |
| 2 | B (H) | antibody hu5B3.v2 Fab heavy chain | polymer | 228 | 24653.5 | 1 | Homo sapiens (human) | ||
| 3 | C (L) | antibody hu5B3.v2 Fab light chain | polymer | 218 | 23767.3 | 1 | Homo sapiens (human) | ||
| 4 | D, E, H (H, L) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | F, G (L) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | I, J, K (A, H, L) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A: 412 - 423 (UniProt: Q9YK84)
| PDB | External Database | Details |
|---|---|---|
| Gly 424 | - | expression tag |
| Ser 425 | - | expression tag |
| Gly 426 | - | expression tag |
| Lys 427 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 50148.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 468.4 | |
| All* | Total formula weight | 50617.0 |
