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4HQU

Crystal structure of human PDGF-BB in complex with a modified nucleotide aptamer (SOMAmer SL5)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Platelet-derived growth factor subunit Bpolymer10912313.51UniProt (P01127)
Pfam (PF00341)
Homo sapiens (human)PDGF subunit B, PDGF-2, Platelet-derived growth factor B chain, Platelet-derived growth factor beta polypeptide, Proto-oncogene c-Sis
2B
(C)
SOMAmer SL5polymer248564.01
3C
(C)
SODIUM IONnon-polymer23.01Chemie (NA)
4D
(C)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5E, F
(A, C)
waterwater18.082Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight20877.5
Non-Polymers*Number of molecules2
Total formula weight47.3
All*Total formula weight20924.8
*Water molecules are not included.

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PDB entries from 2026-02-04

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