4HQJ

Crystal structure of Na+,K+-ATPase in the Na+-bound state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Sodium/potassium-transporting ATPase subunit alpha-1	polymer	1021	112797.6	2	UniProt (P05024) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF00702) Pfam (PF00689) In PDB	Sus scrofa (pigs)	Na(+)/K(+) ATPase alpha-1 subunit, Sodium pump subunit alpha-1
2	B, D	Sodium/potassium-transporting ATPase subunit beta-1	polymer	303	35144.3	2	UniProt (P05027) Pfam (PF00287) In PDB	Sus scrofa (pigs)	Sodium/potassium-dependent ATPase subunit beta-1
3	G, E	Na+/K+ ATPase gamma subunit transcript variant a	polymer	65	7094.1	2	UniProt (Q58K79) Pfam (PF02038) In PDB	Sus scrofa (pigs)
4	A, C	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
5	A, C	TETRAFLUOROALUMINATE ION	non-polymer		103.0	2	Chemie (ALF)
6	A, C	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
7	A, C	SODIUM ION	non-polymer		23.0	6	Chemie (NA)
8	A, C, D	CHOLESTEROL	non-polymer		386.7	5	Chemie (CLR)

Sequence modifications

B, D: 1 - 303 (UniProt: P05027)

PDB	External Database	Details
Ser 151	Phe 151	SEE REMARK 999

G, E: 1 - 65 (UniProt: Q58K79)

PDB	External Database	Details
Leu 45	Ile 45	CONFLICT

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	310072.0
Non-Polymers*	Number of molecules	17
	Total formula weight	3180.2
All*	Total formula weight	313252.2

*Water molecules are not included.