4HPX
Crystal structure of Tryptophan Synthase at 1.65 A resolution in complex with alpha aminoacrylate E(A-A) and benzimidazole in the beta site and the F9 inhibitor in the alpha site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tryptophan synthase alpha chain | polymer | 268 | 28698.8 | 1 | UniProt (P00929) Pfam (PF00290) | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 2 | B (B) | Tryptophan synthase beta chain | polymer | 397 | 42918.9 | 1 | UniProt (P0A2K1) Pfam (PF00291) | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 3 | C (A) | 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE | non-polymer | 365.2 | 1 | Chemie (F9F) | |||
| 4 | D, L, M, N, O (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 5 | E, F, G (B) | BENZIMIDAZOLE | non-polymer | 118.1 | 3 | Chemie (BZI) | |||
| 6 | H (B) | 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid | non-polymer | 316.2 | 1 | Chemie (0JO) | |||
| 7 | I, J, K (B) | BICINE | non-polymer | 163.2 | 3 | Chemie (BCN) | |||
| 8 | P, Q (B) | CESIUM ION | non-polymer | 132.9 | 2 | Chemie (CS) | |||
| 9 | R, S (A, B) | water | water | 18.0 | 722 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71617.7 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2321.8 | |
| All* | Total formula weight | 73939.4 |
