4HKZ
Trastuzumab Fab complexed with Protein L and Protein A fragments
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Trastuzumab light chain | polymer | 213 | 23362.9 | 1 | Homo sapiens | ||
| 2 | B (B) | Trastuzumab heavy chain | polymer | 221 | 23554.4 | 1 | Homo sapiens | ||
| 3 | C (H) | Immunoglobulin G-binding protein A | polymer | 54 | 6037.5 | 1 | UniProt (P0A015) Pfam (PF02216) | Staphylococcus aureus | IgG-binding protein A, Staphylococcal protein A |
| 4 | D (E) | Protein L fragment | polymer | 63 | 6850.6 | 1 | Pfam (PF02246) UniProt (by SIFTS) (Q51918) | FINEGOLDIA MAGNA | |
| 5 | E (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | F, G, H, I (A, B, H, E) | water | water | 18.0 | 557 | Chemie (HOH) |
Sequence modifications
H: 4 - 54 (UniProt: P0A015)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Tyr 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 59805.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 59840.8 |
