4HJS
Kinetic stabilization of transthyretin through covalent modification of K15 by (E)-N-(4-(4-hydroxy-3,5-dimethylstyryl)ethanesulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transthyretin | polymer | 116 | 12703.2 | 2 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (human) | ATTR, Prealbumin, TBPA |
| 2 | C, D (A, B) | N-{4-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]phenyl}ethanesulfonamide | non-polymer | 331.4 | 2 | Chemie (18J) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25406.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 662.9 | |
| All* | Total formula weight | 26069.3 |
