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4HIX

Crystal structure of a humanised 3D6 Fab bound to amyloid beta peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
Humanized 3D6 Fab heavy chainpolymer22724264.11Pfam (PF07654)
UniProt (by SIFTS) (P01857)
homo Sapiens Mus musculus (human mouse)
2B
(L)
Humanized 3D6 Fab light chainpolymer22024162.01Pfam (PF07654)
UniProt (by SIFTS) (P01834)
homo Sapiens Mus musculus (human mouse)
3C
(A)
Beta-amyloid protein 40polymer283268.51UniProt (P05067)
Pfam (PF03494)
Homo sapiensBeta-APP40
4D, E, F
(H, L, A)
waterwater18.0237Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight51694.5
All*Total formula weight51694.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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