4HI9

1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at wavelength 0.91974

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Integrin-linked protein kinase	polymer	179	20256.9	1	UniProt (Q13418) Pfam (PF12796)	Homo sapiens (human)	59 kDa serine/threonine-protein kinase, ILK-1, ILK-2, p59ILK
2	B (B)	LIM and senescent cell antigen-like-containing domain protein 1	polymer	72	8288.2	1	UniProt (P48059) Pfam (PF00412)	Homo sapiens (human)	Particularly interesting new Cys-His protein 1, PINCH-1, Renal carcinoma antigen NY-REN-48
3	C (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
4	D, E, F, G, H... (A, B)	IODIDE ION	non-polymer		126.9	10	Chemie (IOD)
5	L, M (B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
6	P, Q (A, B)	water	water		18.0	221	Chemie (HOH)

Sequence modifications

A: 1 - 174 (UniProt: Q13418)

PDB	External Database	Details
Gly -4	-	expression tag
Ser -3	-	expression tag
Pro -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

B: 6 - 68 (UniProt: P48059)

PDB	External Database	Details
Ser -3	-	expression tag
Glu -2	-	expression tag
Asn -1	-	expression tag
Leu 0	-	expression tag
Tyr 1	-	expression tag
Phe 2	-	expression tag
Gln 3	-	expression tag
Gly 4	-	expression tag
Ser 5	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28545.1
Non-Polymers*	Number of molecules	13
	Total formula weight	1494.8
All*	Total formula weight	30039.9

*Water molecules are not included.