4HGE
JAK2 kinase (JH1 domain) in complex with compound 8
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Tyrosine-protein kinase JAK2 | polymer | 300 | 35342.1 | 2 | UniProt (O60674) Pfam (PF07714) In PDB | Homo sapiens (human) | Janus kinase 2, JAK-2 |
2 | A, B | N-[1-(3-chlorophenyl)-3-methyl-1H-pyrazol-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | non-polymer | 352.8 | 2 | Chemie (15V) | |||
3 | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 70684.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 705.6 | |
All* | Total formula weight | 71389.8 |