4HAN

Crystal structure of Galectin 8 with NDP52 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Galectin-8	polymer	293	33222.2	2	UniProt (O00214) Pfam (PF00337) In PDB	Homo sapiens (human)
2	C, D	Calcium-binding and coiled-coil domain-containing protein 2	polymer	14	1465.6	2	UniProt (Q13137) In PDB	Homo sapiens (human)	Antigen nuclear dot 52 kDa protein, Nuclear domain 10 protein NDP52, Nuclear domain 10 protein 52, Nuclear dot protein 52
3	A, B	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
4	A, B	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	3	Chemie (PEG)
5		water	water		18.0	351	Chemie (HOH)

Sequence modifications

A, B: 1 - 155 (UniProt: O00214)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag
Val 56	Met 56	conflict

A, B: 184 - 317 (UniProt: O00214)

PDB	External Database	Details
His 156	-	linker
Met 157	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	69375.5
Non-Polymers*	Number of molecules	5
	Total formula weight	1645.2
All*	Total formula weight	71020.8

*Water molecules are not included.