4H6D
Crystal structure of PLP-soaked HMP synthase Thi5 from S. cerevisiae
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | F, A, B, C, D... | Pyrimidine precursor biosynthesis enzyme THI5 | polymer | 346 | 39415.6 | 8 | UniProt (P43534) Pfam (PF09084) In PDB | Saccharomyces cerevisiae (yeast) | HMP synthase Thi5 |
2 | A, B, E, H | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 4 | Chemie (PLP) |
Sequence modifications
F, A, B, C, D, E, G, H: 1 - 340 (UniProt: P43534)
PDB | External Database | Details |
---|---|---|
Lys 101 | Glu 101 | engineered mutation |
Ser 102 | Asp 102 | engineered mutation |
Thr 317 | Gln 317 | engineered mutation |
His 341 | - | expression tag |
His 342 | - | expression tag |
His 343 | - | expression tag |
His 344 | - | expression tag |
His 345 | - | expression tag |
His 346 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 315324.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 988.6 | |
All* | Total formula weight | 316313.3 |