4H26
TCR interaction with peptide mimics of nickel offers structure insight to nickel contact allergy
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | HLA class II histocompatibility antigen, DR alpha chain | polymer | 179 | 20842.5 | 2 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (human) | MHC class II antigen DRA |
| 2 | B, E (B, E) | MHC class II antigen | polymer | 188 | 21936.6 | 2 | UniProt (B8YAC7) Pfam (PF00969) Pfam (PF07654) | Homo sapiens (human) | MHC class II antigen DRB3 |
| 3 | C, F (C, F) | peptide | polymer | 11 | 1425.7 | 2 | |||
| 4 | G, H (G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | I, J, K, L, M... (A, B, C, D, E...) | water | water | 18.0 | 174 | Chemie (HOH) |
Sequence modifications
B, E: 6 - 188 (UniProt: B8YAC7)
| PDB | External Database | Details |
|---|---|---|
| Thr 3 | - | expression tag |
| Arg 4 | - | expression tag |
| Pro 5 | - | expression tag |
| Thr 77 | Asn 72 | conflict |
| Arg 189 | - | expression tag |
| Ala 190 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 88409.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| All* | Total formula weight | 89258.4 |
