4H22

Crystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor LRRFIP1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Leucine-rich repeat flightless-interacting protein 1	polymer	103	12399.9	4	UniProt (Q32MZ4)	Homo sapiens (human)	LRR FLII-interacting protein 1, GC-binding factor 2, TAR RNA-interacting protein
2	E, F, G, H (A, B, C, D)	water	water		18.0	26	Chemie (HOH)

Sequence modifications

A, B, C, D: 162 - 249 (UniProt: Q32MZ4)

PDB	External Database	Details
Met 161	-	expression tag
Pro 250	-	expression tag
Lys 251	-	expression tag
Leu 252	-	expression tag
Ala 253	-	expression tag
Ala 254	-	expression tag
Ala 255	-	expression tag
Leu 256	-	expression tag
Glu 257	-	expression tag
His 258	-	expression tag
His 259	-	expression tag
His 260	-	expression tag
His 261	-	expression tag
His 262	-	expression tag
His 263	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	49599.8
All*	Total formula weight	49599.8

*Water molecules are not included.