4GZ3

Crystal structure of human O-GlcNAc Transferase with UDP and a thioglycopeptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit	polymer	723	80974.5	2	UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844)	Homo sapiens (human)	O-GlcNAc transferase subunit p110, O-linked N-acetylglucosamine transferase 110 kDa subunit, OGT
2	B, D (B, D)	Casein kinase II subunit alpha	polymer	14	1398.6	2	UniProt (P68400)	Homo sapiens	CK II alpha
3	E, I (A, C)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	2	Chemie (UDP)
4	F, H, K (A, B, D)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
5	G, J (B, D)	2-acetamido-2-deoxy-5-thio-beta-D-glucopyranose	non-polymer		237.3	2	Chemie (0YT)
6	L, M, N, O (A, B, C, D)	water	water		18.0	836	Chemie (HOH)

Sequence modifications

A, C: 313 - 1031 (UniProt: O15294)

PDB	External Database	Details
Gly 309	-	expression tag
Pro 310	-	expression tag
Gly 311	-	expression tag
Ser 312	-	expression tag

B, D: 14 - 26 (UniProt: P68400)

PDB	External Database	Details
Tyr 13	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	164746.1
Non-Polymers*	Number of molecules	7
	Total formula weight	1571.1
All*	Total formula weight	166317.2

*Water molecules are not included.