4GZ3

Crystal structure of human O-GlcNAc Transferase with UDP and a thioglycopeptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006493	biological_process	protein O-linked glycosylation
A	0016757	molecular_function	glycosyltransferase activity
C	0006493	biological_process	protein O-linked glycosylation
C	0016757	molecular_function	glycosyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphothreonine; by CDK1 => ECO:0000269|PubMed:7592773

Chain	Residue	Details
B	THR18
D	THR18

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:23103939, ECO:0007744|PDB:4GYW

Chain	Residue	Details
A	GLN839
C	HIS901
C	HIS920
C	ASP925
A	LYS842
A	ALA896
A	HIS901
A	HIS920
A	ASP925
C	GLN839
C	LYS842
C	ALA896

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphothreonine; by AMPK => ECO:0000269|PubMed:24563466, ECO:0000269|PubMed:37541260

Chain	Residue	Details
A	THR444
C	THR444

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site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P56558

Chain	Residue	Details
A	TYR979
C	TYR979

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site_id	SWS_FT_FI5
Number of Residues	2
Details	CARBOHYD: O-linked (GlcNAc) serine; by autocatalysis => ECO:0000269|PubMed:27713473

Chain	Residue	Details
A	SER389
C	SER389

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