4GYU
Crystal Structure of New Delhi Metallo-beta-Lactamase-1 A121F mutant from Klebsiella pneumoniae
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase NDM-1 | polymer | 243 | 25794.0 | 1 | UniProt (C7C422) Pfam (PF00753) | Klebsiella pneumoniae | NDM-1, Metallo-beta-lactamase NDM-1 |
| 2 | B, C (A) | IMIDAZOLE | non-polymer | 69.1 | 2 | Chemie (IMD) | |||
| 3 | D (A) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
| 4 | E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | F, G (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | H (A) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A: 31 - 270 (UniProt: C7C422)
| PDB | External Database | Details |
|---|---|---|
| Ser 28 | - | expression tag |
| Asn 29 | - | expression tag |
| Ala 30 | - | expression tag |
| Phe 121 | Ala 121 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25794.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 710.8 | |
| All* | Total formula weight | 26504.8 |
