4GYQ
Crystal Structure of New Delhi Metallo-beta-Lactamase-1 D223A mutant from Klebsiella pneumoniae
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Beta-lactamase NDM-1 | polymer | 243 | 25673.9 | 4 | UniProt (C7C422) | Klebsiella pneumoniae | NDM-1, Metallo-beta-lactamase NDM-1 |
| 2 | E, F, G (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 3 | H (C) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 1049 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 31 - 270 (UniProt: C7C422)
| PDB | External Database | Details |
|---|---|---|
| Ser 28 | - | expression tag |
| Asn 29 | - | expression tag |
| Ala 30 | - | expression tag |
| Ala 223 | Asp 223 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 102695.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 210.5 | |
| All* | Total formula weight | 102906.1 |
