4GXS

Ligand binding domain of GluA2 (AMPA/glutamate receptor) bound to (-)-kaitocephalin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, D)	Glutamate receptor 2	polymer	258	28835.3	2	UniProt (P19491) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (brown rat rat rats)	GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2
2	C, E (B, D)	(5R)-2-[(1S,2R)-2-amino-2-carboxy-1-hydroxyethyl]-5-{(2S)-2-carboxy-2-[(3,5-dichloro-4-hydroxybenzoyl)amino]ethyl}-L-proline	non-polymer		494.3	2	Chemie (0YS)
3	D, F, G (B, D)	ZINC ION	non-polymer		65.4	3	Chemie (ZN)
4	H, I (B, D)	water	water		18.0	376	Chemie (HOH)

Sequence modifications

B, D: 4 - 117 (UniProt: P19491)
B, D: 120 - 261 (UniProt: P19491)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57670.6
Non-Polymers*	Number of molecules	5
	Total formula weight	1184.8
All*	Total formula weight	58855.4

*Water molecules are not included.