4GV7
Human ARTD1 (PARP1) - Catalytic domain in complex with inhibitor ME0328
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Poly [ADP-ribose] polymerase 1 | polymer | 358 | 40199.9 | 4 | UniProt (P09874) Pfam (PF02877) Pfam (PF00644) In PDB | Homo sapiens (human) | PARP-1 |
2 | A, B, C, D | 2-methylquinazolin-4(3H)-one | non-polymer | 160.2 | 4 | Chemie (MEW) |
Sequence modifications
A, B, C, D: 662 - 1011 (UniProt: P09874)
PDB | External Database | Details |
---|---|---|
Met 661 | - | expression tag |
Ala 762 | Val 762 | SEE REMARK 999 |
Ala 1012 | - | expression tag |
His 1013 | - | expression tag |
His 1014 | - | expression tag |
His 1015 | - | expression tag |
His 1016 | - | expression tag |
His 1017 | - | expression tag |
His 1018 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 160799.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 640.7 | |
All* | Total formula weight | 161440.5 |