4GV4
Human ARTD3 (PARP3) - Catalytic domain in complex with inhibitor ME0328
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Poly [ADP-ribose] polymerase 3 | polymer | 357 | 39752.1 | 1 | UniProt (Q9Y6F1) Pfam (PF02877) Pfam (PF00644) In PDB | Homo sapiens (human) | PARP-3 |
| 2 | A | 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[(1S)-1-phenylethyl]propanamide | non-polymer | 321.4 | 1 | Chemie (MEJ) | |||
| 3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence modifications
A: 178 - 532 (UniProt: Q9Y6F1)
| PDB | External Database | Details |
|---|---|---|
| Ser 176 | - | expression tag |
| Met 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39752.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 399.5 | |
| All* | Total formula weight | 40151.6 |
