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4GV1

PKB alpha in complex with AZD5363

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ARAC-alpha serine/threonine-protein kinasepolymer34039393.91UniProt (P31749)
Pfam (PF00069)
Pfam (PF00433)
In PDB
Homo sapiens (human)Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha
2A4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamidenon-polymer428.91Chemie (0XZ)
3AGLYCEROLnon-polymer92.14Chemie (GOL)
4waterwater18.0393Chemie (HOH)
Sequence modifications
A: 144 - 480 (UniProt: P31749)
PDBExternal DatabaseDetails
Leu 141-EXPRESSION TAG
Gly 142-EXPRESSION TAG
Ser 143-EXPRESSION TAG
Asp 473Ser 473CONFLICT
Ser 478Gly 478CONFLICT
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39393.9
Non-Polymers*Number of molecules5
Total formula weight797.3
All*Total formula weight40191.1
*Water molecules are not included.

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PDB entries from 2024-09-18

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