4GV1
PKB alpha in complex with AZD5363
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | RAC-alpha serine/threonine-protein kinase | polymer | 340 | 39393.9 | 1 | UniProt (P31749) Pfam (PF00069) Pfam (PF00433) In PDB | Homo sapiens (human) | Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha |
2 | A | 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide | non-polymer | 428.9 | 1 | Chemie (0XZ) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
4 | water | water | 18.0 | 393 | Chemie (HOH) |
Sequence modifications
A: 144 - 480 (UniProt: P31749)
PDB | External Database | Details |
---|---|---|
Leu 141 | - | EXPRESSION TAG |
Gly 142 | - | EXPRESSION TAG |
Ser 143 | - | EXPRESSION TAG |
Asp 473 | Ser 473 | CONFLICT |
Ser 478 | Gly 478 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 39393.9 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 797.3 | |
All* | Total formula weight | 40191.1 |