4GUK
New crystal form structure of human NCS1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, B, D) | Neuronal calcium sensor 1 | polymer | 190 | 21902.7 | 4 | UniProt (P62166) Pfam (PF00036) Pfam (PF13499) | Homo sapiens (human) | NCS-1, Frequenin homolog, Frequenin-like protein, Frequenin-like ubiquitous protein |
| 2 | CA, E, F, JA, KA... (B, A, D, C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 7 | Chemie (PG4) | |||
| 3 | G, H, HA, I, Z (A, D, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | EA, FA, GA, J, K... (D, A, C, B) | CALCIUM ION | non-polymer | 40.1 | 12 | Chemie (CA) | |||
| 5 | DA, LA, M, T (B, D, A, C) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 6 | O (C) | 3,6,9,12,15-PENTAOXAHEPTADECANE | non-polymer | 250.3 | 1 | Chemie (P3G) | |||
| 7 | AA, BA, IA, S (B, D, C) | (2S,4R,6R,6AS)-4-(2-AMINO-6-OXO-1,6-DIHYDROPURIN-9-YL)-6-(HYDROXYMETHYL)-TETRAHYDROFURO[3,4-D][1,3]DIOXOL-2-YLPHOSPHONI C ACID | non-polymer | 375.2 | 4 | Chemie (P2G) | |||
| 8 | Y (B) | ALANINE | non-polymer | 89.1 | 1 | Chemie (ALA) | |||
| 9 | MA, NA, OA, PA (A, C, B, D) | water | water | 18.0 | 374 | Chemie (HOH) |
Sequence modifications
A, C, B, D: 6 - 188 (UniProt: P62166)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gly 2 | - | expression tag |
| Lys 3 | - | expression tag |
| Ser 4 | - | expression tag |
| Asn 5 | - | expression tag |
| Leu 189 | - | expression tag |
| Val 190 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 87610.7 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 4083.2 | |
| All* | Total formula weight | 91693.8 |
