4GU9
Focal adhesion kinase catalytic domain in complex with (2-Fluoro-phenyl)-(1H-pyrazolo[3,4-d]pyrimidin-4-yl)-amine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Focal adhesion kinase 1 | polymer | 279 | 31957.9 | 2 | UniProt (Q05397) Pfam (PF07714) In PDB | Homo sapiens (human) | FADK 1, Focal adhesion kinase-related nonkinase, FRNK, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK, pp125FAK |
2 | A, B | N-(2-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | non-polymer | 229.2 | 2 | Chemie (4GU) | |||
3 | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A, B: 410 - 686 (UniProt: Q05397)
PDB | External Database | Details |
---|---|---|
Gly 408 | - | expression tag |
Ser 409 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 63915.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 458.4 | |
All* | Total formula weight | 64374.3 |