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4GU3

Crystal structure of the T1L reovirus attachment protein sigma1 in complex with the GM2 glycan

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Outer capsid protein sigma-1polymer21924500.53UniProt (P04506)
Pfam (PF01664)
Mammalian orthoreovirus 1 (T1L)Sigma1, Cell attachment protein, Hemagglutinin
2D, E, F
(D, E, F)
N-acetyl-alpha-neuraminic acid-(2-3)-[2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranosebranched836.73In PDB
GlyTouCan (G79389NT)
Sequence modifications
A, B, C: 261 - 470 (UniProt: P04506)
PDBExternal DatabaseDetails
Gly 252-expression tag
Val 253-expression tag
Leu 254-expression tag
Asn 255-expression tag
Gln 256-expression tag
Gly 257-expression tag
Val 258-expression tag
Thr 259-expression tag
Ser 260-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight73501.4
BranchedNumber of molecules3
Total formula weight2510.2
All*Total formula weight76011.6
*Water molecules are not included.

246333

PDB entries from 2025-12-17

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