4GTY
Crystal structure of mouse Enpp1 in complex with GMP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Alkaline phosphodiesterase I | polymer | 823 | 94560.2 | 2 | UniProt (Q9R1E6) UniProt (G3X9S2) Pfam (PF01033) Pfam (PF01663) Pfam (PF01223) UniProt (by SIFTS) (P06802) In PDB | Mus musculus | E-NPP 2, Autotaxin, Extracellular lysophospholipase D, LysoPLD, Ectonucleotide pyrophosphatase/phosphodiesterase 1, isoform CRA_d |
2 | C | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G09724ZC) | |||
3 | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
4 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
5 | A, B | GUANOSINE-5'-MONOPHOSPHATE | non-polymer | 363.2 | 2 | Chemie (5GP) | |||
6 | A, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
7 | A, B | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) |
Sequence modifications
A, B: 51 - 59 (UniProt: Q9R1E6)
A, B: 92 - 905 (UniProt: G3X9S2)
PDB | External Database | Details |
---|---|---|
Arg 59 | Lys 59 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 189120.4 | |
Branched | Number of molecules | 2 |
Total formula weight | 1497.4 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1953.1 | |
All* | Total formula weight | 192570.8 |