4GTP
FTase in complex with BMS analogue 16
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | polymer | 377 | 44098.1 | 1 | UniProt (Q04631) Pfam (PF01239) In PDB | Rattus norvegicus (rat) | CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha |
2 | B | Protein farnesyltransferase subunit beta | polymer | 427 | 47749.3 | 1 | UniProt (Q02293) Pfam (PF00432) In PDB | Rattus norvegicus (rat) | FTase-beta, CAAX farnesyltransferase subunit beta, Ras proteins prenyltransferase subunit beta |
3 | A, B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
4 | B | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | B | FARNESYL DIPHOSPHATE | non-polymer | 382.3 | 1 | Chemie (FPP) | |||
6 | B | 5-{(3R)-3-(4-hydroxybenzyl)-4-[(4-methoxyphenyl)sulfonyl]-1-[(1-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-7-yl}furan-2-carbaldehyde | non-polymer | 612.7 | 1 | Chemie (7TP) | |||
7 | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 91847.5 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1373.0 | |
All* | Total formula weight | 93220.4 |