4GTO
FTase in complex with BMS analogue 14
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | polymer | 377 | 44098.1 | 1 | UniProt (Q04631) Pfam (PF01239) | Rattus norvegicus (rat) | CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha |
| 2 | B (B) | Protein farnesyltransferase subunit beta | polymer | 427 | 47749.3 | 1 | UniProt (Q02293) Pfam (PF00432) | Rattus norvegicus (rat) | FTase-beta, CAAX farnesyltransferase subunit beta, Ras proteins prenyltransferase subunit beta |
| 3 | C (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (B) | 4-({(3R)-7-cyano-4-[(4-methoxyphenyl)sulfonyl]-1-[(1-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-3-yl}methyl)phenyl trifluoromethanesulfonate | non-polymer | 675.7 | 1 | Chemie (7TO) | |||
| 5 | E (B) | FARNESYL DIPHOSPHATE | non-polymer | 382.3 | 1 | Chemie (FPP) | |||
| 6 | F (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 7 | G, H (A, B) | water | water | 18.0 | 562 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91847.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1201.6 | |
| All* | Total formula weight | 93049.1 |
