4GTB
T. Maritima FDTS with FAD, dUMP, and Raltitrexed.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thymidylate synthase thyX | polymer | 232 | 27503.7 | 1 | UniProt (Q9WYT0) Pfam (PF02511) | Thermotoga maritima | TS, TSase |
| 2 | B (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 3 | C (A) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 1 | Chemie (UMP) | |||
| 4 | D (A) | TOMUDEX | non-polymer | 458.5 | 1 | Chemie (D16) | |||
| 5 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | F (A) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A: 1 - 220 (UniProt: Q9WYT0)
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Asp -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Ile -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27503.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1587.7 | |
| All* | Total formula weight | 29091.4 |
