4GSR

Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Probable conserved lipoprotein LPPS	polymer	287	31280.7	1	UniProt (O53223) Pfam (PF17964) Pfam (PF03734) In PDB	Mycobacterium tuberculosis	LdtMt2
2	A	2-(ETHYLMERCURI-THIO)-BENZOIC ACID	non-polymer		382.8	1	Chemie (EMT)
3	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4		water	water		18.0	230	Chemie (HOH)

Sequence modifications

A: 131 - 408 (UniProt: O53223)

PDB	External Database	Details
Met 130	-	expression tag
Leu 409	-	expression tag
Glu 410	-	expression tag
His 411	-	expression tag
His 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	31280.7
Non-Polymers*	Number of molecules	3
	Total formula weight	567.0
All*	Total formula weight	31847.7

*Water molecules are not included.