4GRU
crystallographic and biological characterization of N- and C- terminus mutants of human MIF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Macrophage migration inhibitory factor | polymer | 114 | 12355.1 | 3 | UniProt (P14174) Pfam (PF01187) | Homo sapiens (human) | MIF, Glycosylation-inhibiting factor, GIF, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase |
| 2 | D, E, F, G, H... (A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 12 | Chemie (CL) | |||
| 3 | I, P, T (A, B, C) | 1,4-DIETHYLENE DIOXIDE | non-polymer | 88.1 | 3 | Chemie (DIO) | |||
| 4 | J, Q (B, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | U, V, W (A, B, C) | water | water | 18.0 | 319 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37065.2 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 881.9 | |
| All* | Total formula weight | 37947.0 |
