4GRQ
Characterization of N- and C- terminus mutants of human MIF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Macrophage migration inhibitory factor | polymer | 116 | 12497.2 | 3 | UniProt (P14174) Pfam (PF01187) | Homo sapiens (human) | MIF, Glycosylation-inhibiting factor, GIF, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase |
| 2 | D, E, G, H, I... (A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 3 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | K (C) | 2-methyl-1-[2-(propan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one | non-polymer | 230.3 | 1 | Chemie (AVL) | |||
| 5 | L, M, N (A, B, C) | water | water | 18.0 | 505 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 116 (UniProt: P14174)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | - | insertion |
| Ala 3 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37491.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 539.1 | |
| All* | Total formula weight | 38030.7 |
