4GNF
Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-15
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Histone-lysine N-methyltransferase NSD3 | polymer | 107 | 12058.8 | 1 | UniProt (Q9BZ95) Pfam (PF17982) In PDB | Homo sapiens | Nuclear SET domain-containing protein 3, Protein whistle, WHSC1-like 1 isoform 9 with methyltransferase activity to lysine, Wolf-Hirschhorn syndrome candidate 1-like protein 1, WHSC1-like protein 1 |
| 2 | C | Histone H3.3 | polymer | 15 | 1565.8 | 1 | UniProt (P84243) In PDB | Homo sapiens | |
| 3 | A | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
A: 1310 - 1413 (UniProt: Q9BZ95)
| PDB | External Database | Details |
|---|---|---|
| Ser 1307 | - | expression tag |
| Asn 1308 | - | expression tag |
| Ala 1309 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 13624.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 13886.2 |
