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4GLS

Crystal Structure of Chemically Synthesized Heterochiral {D-Protein Antagonist plus VEGF-A} Protein Complex in space group P21

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
D- Vascular endothelial growth factor-Apolymer10211942.62
2C, H
(C, G)
L- RFX001polymer566379.92
3D, G
(D, H)
D- RFX001polymer566375.92
4E, F
(E, F)
Vascular endothelial growth factor Apolymer10211948.72UniProt (P15692)
Pfam (PF00341)
Homo sapiensVEGF-A, Vascular permeability factor, VPF
5I
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
6J
(F)
GLYCEROLnon-polymer92.11Chemie (GOL)
7K, L, M, N, O...
(A, B, C, D, E...)
waterwater18.01042Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight73294.2
Non-Polymers*Number of molecules2
Total formula weight198.2
All*Total formula weight73492.4
*Water molecules are not included.

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PDB entries from 2025-07-16

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