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4GL5

Structure of human placental aromatase complexed with designed inhibitor HDDG029 (compound 4)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cytochrome P450 19A1polymer50357954.91UniProt (P11511)
Pfam (PF00067)
Homo sapiens (human)Aromatase, CYPXIX, Cytochrome P-450AROM, Estrogen synthase
2B
(A)
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.51Chemie (HEM)
3C
(A)
(6alpha,8alpha)-6-(but-2-yn-1-yloxy)androsta-1,4-diene-3,17-dionenon-polymer352.51Chemie (G29)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight57954.9
Non-Polymers*Number of molecules2
Total formula weight969.0
All*Total formula weight58923.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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