4GH9

Crystal structure of Marburg virus VP35 RNA binding domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Polymerase cofactor VP35	polymer	146	16302.6	1	UniProt (P35259) Pfam (PF02097)	Marburg virus (MARV)
2	B, C, D, E, F... (A)	ACETATE ION	non-polymer		59.0	6	Chemie (ACT)
3	H (A)	water	water		18.0	117	Chemie (HOH)

Sequence modifications

A: 204 - 329 (UniProt: P35259)

PDB	External Database	Details
Met 184	-	expression tag
Ala 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag
Val 192	-	expression tag
Asp 193	-	expression tag
Asp 194	-	expression tag
Asp 195	-	expression tag
Asp 196	-	expression tag
Lys 197	-	expression tag
Glu 198	-	expression tag
Asn 199	-	expression tag
Leu 200	-	expression tag
Tyr 201	-	expression tag
Phe 202	-	expression tag
Gln 203	-	expression tag
Cys 296	Ser 296	variant

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	16302.6
Non-Polymers*	Number of molecules	6
	Total formula weight	354.3
All*	Total formula weight	16656.9

*Water molecules are not included.