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4GGD

Structural analysis of human Cdc20 supports multisite degron recognition by APC/C.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Cell division cycle protein 20 homologpolymer43147495.32UniProt (Q12834)
Pfam (PF12894)
Pfam (PF00400)
Homo sapiens (human)p55CDC
2C, D
(C, D)
Mitotic checkpoint serine/threonine-protein kinase BUB1 betapolymer232761.12UniProt (O60566)Homo sapiensMAD3/BUB1-related protein kinase, hBUBR1, Mitotic checkpoint kinase MAD3L, Protein SSK1
3E, F, G
(A, B, D)
waterwater18.0185Chemie (HOH)
Sequence modifications
A, B: 71 - 499 (UniProt: Q12834)
PDBExternal DatabaseDetails
Gly 69-expression tag
Ala 70-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight100512.7
All*Total formula weight100512.7
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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