4GGD
Structural analysis of human Cdc20 supports multisite degron recognition by APC/C.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0010997 | molecular_function | anaphase-promoting complex binding |
| A | 0097027 | molecular_function | ubiquitin-protein transferase activator activity |
| A | 1904668 | biological_process | positive regulation of ubiquitin protein ligase activity |
| B | 0010997 | molecular_function | anaphase-promoting complex binding |
| B | 0097027 | molecular_function | ubiquitin-protein transferase activator activity |
| B | 1904668 | biological_process | positive regulation of ubiquitin protein ligase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. TGGGtsDrHIRIWNV |
| Chain | Residue | Details |
| A | THR373-VAL387 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 96 |
| Details | Repeat: {"description":"WD 1","evidences":[{"source":"PubMed","id":"27120157","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27509861","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5G04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LCW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 82 |
| Details | Repeat: {"description":"WD 2","evidences":[{"source":"PubMed","id":"27120157","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27509861","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5G04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LCW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 70 |
| Details | Repeat: {"description":"WD 3","evidences":[{"source":"PubMed","id":"27120157","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27509861","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5G04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LCW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 84 |
| Details | Repeat: {"description":"WD 4","evidences":[{"source":"PubMed","id":"27120157","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27509861","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5G04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LCW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 84 |
| Details | Repeat: {"description":"WD 5","evidences":[{"source":"PubMed","id":"27120157","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27509861","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5G04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LCW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 80 |
| Details | Repeat: {"description":"WD 6","evidences":[{"source":"PubMed","id":"27120157","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27509861","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5G04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LCW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 58 |
| Details | Repeat: {"description":"WD 7","evidences":[{"source":"PubMed","id":"27120157","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27509861","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5G04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LCW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
