4GA7

Crystal structure of human serpinB1 mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Leukocyte elastase inhibitor	polymer	389	43938.8	2	UniProt (P30740) Pfam (PF00079)	Homo sapiens (human)	LEI, Monocyte/neutrophil elastase inhibitor, EI, M/NEI, Peptidase inhibitor 2, PI-2, Serpin B1
2	C, D (A, B)	water	water		18.0	17	Chemie (HOH)

Sequence modifications

A, B: 1 - 379 (UniProt: P30740)

PDB	External Database	Details
Met -9	-	expression tag
Gly -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Asp 346	Leu 346	engineered mutation
Asp 347	Met 347	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	87877.5
All*	Total formula weight	87877.5

*Water molecules are not included.