4G8T

Crystal structure of a glucarate dehydratase related protein, from actinobacillus succinogenes, target EFI-502312, with sodium and sulfate bound, ordered loop

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Glucarate dehydratase	polymer	464	51460.3	4	UniProt (A6VQF1) Pfam (PF13378)	Actinobacillus succinogenes
2	E, J, Q, U (A, B, C, D)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3	F, K, R, V (A, B, C, D)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
4	G, H, L, M, N... (A, B, C)	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
5	I (A)	(2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL	non-polymer		154.3	1	Chemie (DTU)
6	P, T, W (B, C, D)	2,3-DIHYDROXY-1,4-DITHIOBUTANE	non-polymer		154.3	3	Chemie (DTT)
7	AA, X, Y, Z (D, A, B, C)	water	water		18.0	1973	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 442 (UniProt: A6VQF1)

PDB	External Database	Details
Met -21	-	initiating methionine
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Leu -9	-	expression tag
Gly -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	205841.1
Non-Polymers*	Number of molecules	19
	Total formula weight	1737.9
All*	Total formula weight	207579.0

*Water molecules are not included.