4G8M
Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the agonist CBG-IV at 2.05A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor 2 | polymer | 263 | 29221.7 | 2 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (brown rat rat rats) | GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2 |
| 2 | C, J (A, B) | (1S,2R)-2-[(S)-amino(carboxy)methyl]cyclobutanecarboxylic acid | non-polymer | 173.2 | 2 | Chemie (G8M) | |||
| 3 | D, E, F, G, K... (A, B) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 4 | H, N, O (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 5 | I, P (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | Q, R (A, B) | water | water | 18.0 | 370 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 114 (UniProt: P19491)
A, B: 117 - 260 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ala -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 115 | - | linker |
| Thr 116 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58443.4 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1309.3 | |
| All* | Total formula weight | 59752.7 |
