4G8L

Active state of intact sensor domain of human RNase L with 2-5A bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	2-5A-dependent ribonuclease	polymer	337	37144.3	4	UniProt (Q05823) Pfam (PF00023)	Homo sapiens (human)	2-5A-dependent RNase, Ribonuclease 4, Ribonuclease L, RNase L
2	E, F, G, H (A, B, C, D)	5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE	non-polymer		1005.6	4	Chemie (25A)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	148577.2
Non-Polymers*	Number of molecules	4
	Total formula weight	4022.5
All*	Total formula weight	152599.8

*Water molecules are not included.