4G8L
Active state of intact sensor domain of human RNase L with 2-5A bound
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 25A A 401 |
| Chain | Residue |
| A | GLU55 |
| A | PHE126 |
| A | GLU131 |
| A | TYR135 |
| A | ARG155 |
| B | MET306 |
| B | ARG309 |
| B | ARG310 |
| B | TYR312 |
| A | GLU57 |
| A | GLY58 |
| A | TRP60 |
| A | ASN65 |
| A | GLN68 |
| A | LYS89 |
| A | ASN91 |
| A | ASP122 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 25A B 401 |
| Chain | Residue |
| A | MET306 |
| A | ARG309 |
| A | ARG310 |
| A | TYR312 |
| B | GLU55 |
| B | GLU57 |
| B | GLY58 |
| B | TRP60 |
| B | ASN65 |
| B | GLN68 |
| B | LYS89 |
| B | ASN91 |
| B | ASP122 |
| B | PHE126 |
| B | GLU131 |
| B | TYR135 |
| B | ARG155 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 25A C 401 |
| Chain | Residue |
| C | GLU55 |
| C | GLU57 |
| C | GLY58 |
| C | TRP60 |
| C | ASN65 |
| C | GLN68 |
| C | LYS89 |
| C | ASP122 |
| C | PHE126 |
| C | GLU131 |
| C | TYR135 |
| C | ARG155 |
| D | MET306 |
| D | ARG309 |
| D | ARG310 |
| D | TYR312 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 25A D 401 |
| Chain | Residue |
| C | MET306 |
| C | ARG309 |
| C | ARG310 |
| C | TYR312 |
| D | GLU55 |
| D | GLU57 |
| D | GLY58 |
| D | TRP60 |
| D | ASN65 |
| D | GLN68 |
| D | LYS89 |
| D | ASP122 |
| D | PHE126 |
| D | GLU131 |
| D | TYR135 |
| D | ARG155 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 116 |
| Details | Repeat: {"description":"ANK 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 116 |
| Details | Repeat: {"description":"ANK 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 116 |
| Details | Repeat: {"description":"ANK 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 116 |
| Details | Repeat: {"description":"ANK 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 132 |
| Details | Repeat: {"description":"ANK 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 120 |
| Details | Repeat: {"description":"ANK 7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 52 |
| Details | Region: {"description":"2-5A binding (P-loop) 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 88 |
| Details | Region: {"description":"2-5A binding (P-loop) 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 90 |
| Details | Repeat: {"description":"ANK 5"} |
| Chain | Residue | Details |
