4G7V
Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (R217E, 2.5 A)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H | fragment antibody heavy chain | polymer | 219 | 23092.6 | 1 | Homo sapiens | ||
2 | L | fragment antibody light chain | polymer | 211 | 23103.7 | 1 | Homo sapiens | ||
3 | S | Voltage-sensor containing phosphatase | polymer | 185 | 21168.7 | 1 | UniProt (Q4W8A1) Pfam (PF00520) UniProt (by SIFTS) (F6XHE4) In PDB | Ciona intestinalis (sea vase yellow sea squirt) | |
4 | H, L, S | LAURYL DIMETHYLAMINE-N-OXIDE | non-polymer | 229.4 | 3 | Chemie (LDA) | |||
5 | L | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
6 | L | SUCCINIC ACID | non-polymer | 118.1 | 1 | Chemie (SIN) | |||
7 | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence modifications
S: 89 - 260 (UniProt: Q4W8A1)
PDB | External Database | Details |
---|---|---|
Met 79 | - | EXPRESSION TAG |
Arg 80 | - | EXPRESSION TAG |
Gly 81 | - | EXPRESSION TAG |
Ser 82 | - | EXPRESSION TAG |
His 83 | - | EXPRESSION TAG |
His 84 | - | EXPRESSION TAG |
His 85 | - | EXPRESSION TAG |
His 86 | - | EXPRESSION TAG |
His 87 | - | EXPRESSION TAG |
His 88 | - | EXPRESSION TAG |
Glu 217 | Arg 217 | ENGINEERED MUTATION |
Lys 261 | - | EXPRESSION TAG |
Leu 262 | - | EXPRESSION TAG |
Asn 263 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 67365.0 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 841.7 | |
All* | Total formula weight | 68206.7 |