4G7V

Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (R217E, 2.5 A)

Functional Information from GO Data

Chain	GOid	namespace	contents
S	0005216	molecular_function	monoatomic ion channel activity
S	0005886	cellular_component	plasma membrane
S	0006811	biological_process	monoatomic ion transport
S	0016020	cellular_component	membrane
S	0030171	molecular_function	voltage-gated proton channel activity
S	0055085	biological_process	transmembrane transport
S	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE LDA H 301

Chain	Residue
H	SER31
H	TYR55

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL L 301

Chain	Residue
L	PRO59
L	PRO59
L	ARG61
L	ARG61

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SIN L 302

Chain	Residue
L	SER67
L	GLY68
L	ASP70
L	PHE71
S	ASP204
S	VAL207
S	GLN208
L	SER30
L	SER65
L	GLY66

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LDA L 303

Chain	Residue
L	SER28
L	SER30
S	TYR200
S	ASP204
S	LDA301

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LDA S 301

Chain	Residue
L	SER53
L	LDA303
S	GLN208
S	GLU209
S	THR210

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR200-HIS206
L	TYR192-HIS198

---